Authors:Thomas O. Joos, Paolo Fortina,
Publisher: Humana Press
Keywords: molecular, medicine, methods, diagnostics, clinical, microarrays
Number of Pages: 288
Published: 2005-06-01
List price: $145.00
ISBN-10: 1588293947
ISBN-13: 9781588293947

Leading academic and industrial investigators surveys the world of microarray technology, describing in step-by-step detail diverse DNA and protein assays in clinical laboratories using state-of-the-art technologies. The advanced tools and methods described are designed for mRNA expression analysis, SNP analysis, identification, and quantification of proteins, and for studies of protein-protein interactions. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind t

Authors:John M. Graham, Joan A. Higgins,
Publisher: Humana Press
Keywords: molecular, biology, methods, function, protocols, architecture, biomembrane
Number of Pages: 380
Published: 1993-11-28
List price: $99.50
ISBN-10: 0896032507
ISBN-13: 9780896032507

This second volume of protocols offers the most comprehensive set of modern analytical techniques available for studying the architecture and function of membranes. It features the application of biochemical, spectroscopic, and fluorimetric methods to the investigation of molecular topology, the dynamic aspects of membrane structure, and ion transport. Antibody technology, analysis of molecules involved in intracellular signaling, and receptor-ligand interactions are also covered.

Authors:Dana Philpott, Frank Ebel,
Publisher: Humana Press
Keywords: methods, molecular, medicine, protocols, coli, toxin, shiga
Number of Pages: 368
Published: 2002-09-26
List price: $130.00
ISBN-10: 0896039390
ISBN-13: 9780896039391

Offers tools for illuminating the molecular and cellular microbiology of STEC’s bacterial pathogenesis, as well as the mechanisms of its toxicity. Features protocols for diagnosis of STEC, methods to uncover the strain, outlines animal models, and creates deletion mutants. Expanded-outline. DNLM: Escherichia coli Infections--pathology.

Authors:Tarun B. Patel, Paul J. Bertics,
Publisher: Humana Press
Keywords: methods, molecular, biology, protocols, epidermal, factor, growth
Number of Pages: 224
Published: 2005-12-15
List price: $104.00
ISBN-10: 1588294218
ISBN-13: 9781588294210

A comprehensive collection of optimized methods for dissecting the mechanisms that control epidermal growth factors (EGF) and their regulators in both normal and pathological states. These readily reproducible techniques range from the study of purified EGF receptor to complex signaling and processing networks in intact cells, including a chapter on the clinical and pharmacological considerations of their use in cancer therapy. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining th

Author: Carole R. Mendelson
Publisher: Humana Press
Keywords: endocrinology, contemporary, synthesis, development, lung, surfactant
Number of Pages: 344
Published: 2000-06-15
List price: $155.00
ISBN-10: 0896036766
ISBN-13: 9780896036765

Univ. of Texas Southwestern, Dallas, TX. Critically reviews the roles of various classes of endocrine, paracrine, and neuroendocrine factors in the regulation of lung development and surfactant production. Illuminates the complex endocrinology of the lung for researchers actively studying hormone action in pulmonary biology and medicine today.

Author: Michael Benatar
Publisher: Humana Press
Keywords: clinical, neurology, analysis, evidence, disease, neuromuscular
Number of Pages: 474
Published: 2006-08-01
List price: $149.00
ISBN-10: 158829627X
ISBN-13: 9781588296276

This volume presents a critical appraisal of the neurological literature on neuromuscular disease from an evidence-based perspective. Writing in a readable, accessible style, the author considers, in detail, a broad range of the published literature relevant not only to questions of treatment, but also to issues of diagnosis and prognosis. Through a series of questions and answers concerning specific neuromuscular disorders, each chapter critiques the best available evidence to illustrate strengths and weaknesses of the data and make the reader aware of the quality of clinical research studies

Author: Peter Bugert
Publisher: Humana Press
Keywords: methods, protocols, biology, molecular, blood, rna, profiling, human, dna
Number of Pages: 344
Published: 2008-10-23
List price: $119.00
ISBN-10: 1934115932
ISBN-13: 9781934115930

Blood samples have consistently proven to be a key source of genetic material for a wide variety of diagnostic or research purposes. In DNA and RNA Profiling in Human Blood: Methods and Protocols, leading international experts contribute both established and recently developed protocols for complex and high-throughput DNA and RNA profiling. Divided into two thorough sections, the volume concentrates on DNA profiling for blood cell antigens through methods on high-throughput multiplex approaches and SNP typing, along with RNA profiling in blood cells addressing certain blood cell types such as